How your immune system leans, from allergies to ongoing inflammation
Pages from an example report made with a sample DNA file.
Turn the DNA file you already have into a ranked list of the foods, nutrients and lifestyle changes to focus on and avoid, with the research behind it linked gene by gene.
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Works with your 23andMe, Ancestry, MyHeritage or other raw DNA file
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How it works
1Buy the report We email you a sign-in link.
2Attach your DNA file It's read on your computer.
3Read your report Your report is ready in a few minutes, as a PDF to keep.
Each purchase includes up to three report runs, for a retry, a lost PDF or an updated version.
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“Excellent, detailed reports with actionable info.”
How this report compares with other DNA tools and chatbots
If you've already run your file through another tool or asked a chatbot, here's what each one gives you, side by side.
What you getWhat to do nextWhen your genes disagreeCan you check it?
Noorns
This report
What you get
A ranked summary of the foods, nutrients and lifestyle changes to focus on and avoid, each with a priority score, weighed across the 78 genes this report reads
What to do next
Food first, with supplements named in the exact form
When your genes disagree
Both scores shown side by side, with what they mean
Can you check it?
The research behind each gene, listed with links at the back
Not from Noorns
A gene lookup tool
What you get
A table of your variants, gene by gene
What to do next
Up to you to work out
When your genes disagree
Up to you to weigh
Can you check it?
Varies by tool
Not from Noorns
An AI chatbot
What you get
A quick answer in plain words to the question you ask
What to do next
Suggestions, which can get a variant wrong
When your genes disagree
Depends on what you ask
Can you check it?
Hard to check
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Real pages from an example report made with a sample DNA file. Yours follows the same order, with your own results.
1
The science behind it, if you want it
The biology of the innate and adaptive immune system, how T helper cells choose their role, and why inflammation sometimes fails to resolve, for when you or your practitioner want to understand the mechanisms.
Chapters in this report
Immunology Of Chronic Illness
As titled in the example report.
2
Your Recommendations Summary
A ranked list of foods, nutrients, and lifestyle factors scored by the combined strength of your genetic signal. The place to start.
AYour Focus list. Foods, nutrients and habits to lean into, with the highest priority at the top. An Avoid list follows.
BThe number in brackets is the item's score. Scores are a priority scale. The more of your genes that point to an item, the higher it ranks. They show you where to start, not a guarantee of results.
CSupplements name the exact form, here pyridoxal 5'-phosphate for vitamin B6, because the form affects how well your body can use it.
DFood sits in the same list. Vitamin A rich meats rank alongside the supplements, so you can start with what you eat.
Talk to your doctor before you start a supplement.
Your foods, rankedABCDCalled “Recommendations Summary” in the reportThe top of a Focus list, with four lettered notes. Your scores will differ. From an example report made with a sample DNA file.
3
Where your genes disagree
Where genes pull in opposite directions on the same intervention, both scores are shown so you and your practitioner can make an informed call.
1Two scores for one item. The Focus score weighs the variants that point toward it, and the Avoid score weighs the ones that point away.
2The higher score shows which way it leans. More of your genes point that way, and the other score still counts.
3What the scores can't tell you. They show genetic tendencies, not how your body is responding today. When the two are close, the report suggests talking that item through with your practitioner before acting on it.
Both scores, shownCalled “Conflicts” in the report
In this example, Quercetin scores 292 for Focus and 11 for Avoid.
It ranks higher on the Focus side, and the Avoid score still counts.
Items that appear in both lists, with both scores side by side. From an example report made with a sample DNA file.
4
One page for each gene
Plain-English explanations of every gene, your specific variants, and the targeted changes tied to each one.
One page per geneYou: the two letters read from the DNA file at that spot. Risk: the letter studies link to the effect described for that gene.From an example report made with a sample DNA file.
5
The research, linked
At the back, the studies behind each gene are listed with their links, gene by gene, so you or your practitioner can read the sources.
Sources for every geneCalled “Appendix & References” in the reportThe references for HIF1A. From an example report made with a sample DNA file.
The genes it reads
This report analyzes 78 genes across these areas.
The attack side: Th1 and Th17
Innate alarms and the inflammasome
The allergy side: Th2 and mast cells
Switching inflammation off
Methylation and B vitamins
Histamine and detoxification
Vitamin A, iron, and the gut
Dietary and metabolic genetics
See every area and gene
The attack side: Th1 and Th17. How strongly you mount the inflammatory response to infection, and whether it tends to overshoot (IFNG, IL-12B, IL-17A, IL-17RA, TNF-alpha, IL-6, JAK2, STAT3).
Innate alarms and the inflammasome. The first-line alarms for infection and damage, including NLRP3, a switch inside cells that can keep inflammation cycling (NLRP3, IL-1B, NFKB1, IRF7, HIF1A, DPP9, CD209).
The allergy side: Th2 and mast cells. The messengers behind antibodies, tissue repair, and allergic inflammation, plus the mast cell's IgE receptor (IL-4, IL-4R, IL-5, IL-13, IL-33, FCER1A).
Switching inflammation off. How well your body winds a response down, through IL-10 and vitamin D (IL-10, VDR, GC, CYP2R1).
Methylation and B vitamins. Which forms of folate, B12, B2, and B6 the report suggests for your variants (MTHFR, MTHFS, MTHFD1, DHFR, SLC19A1, MTR, MTRR, PEMT, BHMT, CBS, COMT, NBPF3).
Histamine and detoxification. How you clear histamine and process compounds from food, the environment, and medicines (AOC1/DAO, HNMT, MAOA, MAOB, ALDH2, FMO3, CYP1A2, NAT1, NAT2, CPS1).
Vitamin A, iron, and the gut. How you activate vitamin A, handle iron, digest lactose, and process oxalate and uric acid (BCO1, HFE, TF, TMPRSS6, FUT2, LCT, AGXT, GRHPR, HOGA1, SPP1, SLC2A9, ABCG2).
Dietary and metabolic genetics. How your body processes fat, cholesterol, and carbohydrate, and the eating pattern the report suggests for your variants (APOE4, FADS1, FADS2, PPARG, PPARA, ADIPOQ, CETP, LIPC, FTO, LEPR, ACE, and more).
Is it right for you
Who it's for, and what it doesn't do
Who it's for
Beyond the symptoms named at the top, this report suits people with a diagnosis who want a nutrition plan for their care team, and practitioners designing a protocol.
It shares most of its genes with the MCAS and Histamine Report and adds 14 more, covering the infection-fighting Th1 and Th17 side, first-line alarms such as NLRP3, and IL-10. If mast cell reactions and histamine are your main concern, choose the MCAS and Histamine Report, which adds three genes for mast cell growth and histamine production.
The science, briefly
Why the same anti-inflammatory plan helps one person and not another
If you have cut out foods and added supplements for inflammation and still feel stuck, this report looks at how your genes push on your immune balance.
IL-10 and switching inflammation off
IL-10 helps tell the immune system to stand down. A variant linked to lower IL-10 production in lab tests may leave inflammation running longer.
In your reportYour variants help the report weigh food and lifestyle inputs for this pathway, including fiber and exercise.
Read the full explanation
IL-10 is a messenger that tells the immune system to stand down and helps build regulatory T cells. In lab tests, a variant in its control region was linked to lower IL-10 production, which may leave inflammation running longer. Fiber feeds gut bacteria that make a fatty acid called butyrate, and in a study in mice, butyrate helped form regulatory T cells in the gut. Depending on your variants, the report pairs IL-10 with fiber, garlic, cinnamon, exercise, and meditation.
TNF-alpha and the Western diet
TNF-alpha is an inflammatory messenger. An uncommon variant increased its activity in lab tests, and the report links it to higher inflammation.
In your reportThe report weighs a Mediterranean-style eating pattern and flags a Western diet high in saturated fat and refined carbohydrate for this gene.
Read the full explanation
TNF-alpha is a potent inflammatory messenger. An uncommon TNF-alpha variant made the gene much more active in lab tests, and the report links it to higher inflammation. For this gene the report recommends a Mediterranean-style diet rich in oily fish and fiber, plus foods such as raw crushed garlic, broccoli sprouts, Brazil nuts, and oysters, and flags a Western diet high in saturated fat and refined carbohydrate as raising TNF-alpha.
GC, CYP2R1, VDR and vitamin D
GC carries vitamin D, CYP2R1 starts activating it, and VDR helps cells respond to it. Variants can affect different parts of that pathway.
In your reportThe report puts vitamin D sources in context and ties any supplement dose to a blood test with your doctor.
Read the full explanation
In human immune cells studied in the lab, active vitamin D turned down inflammatory messengers and pushed T cells toward the calming, regulatory role. A study of nearly 34,000 people of European descent linked lower vitamin D levels to common variants in GC, which carries vitamin D in the blood, and near CYP2R1, which starts activating it. VDR is the receptor your cells use to respond to vitamin D. The report names sunlight and oily fish as main sources and ties any supplement dose to a blood test with your doctor.
Those are three of the mechanisms. The report covers 78 genes across eight areas.
More on the science behind this report
This report reads the genes behind your immune balance and suggests foods and nutrients for your variants. It is for people living with inflammation that keeps flaring, autoimmune-like symptoms, allergies that keep widening, or fatigue that never fully lifted after an illness.
Your immune system relies on coordinating cells called T helper cells, and each type has a different job. Th1 cells lead the attack on viruses and bacteria. Th17 cells fight bacteria and fungi and drive strong inflammation. Th2 cells support antibody production and tissue repair, and when they run too hot they are tied to allergies and asthma.
Regulatory T cells, often called Tregs, calm the response down once a threat has passed and help keep it from turning on your own tissue. Immune polarization means the balance tipping toward one of these modes and staying there. Your genes are one of the forces that push it, alongside infections, food, mold, toxins, and body weight.
The same food or supplement can be recommended for one immune pathway and flagged to avoid for another. Green tea is one example in this report. So which suggestions apply depends on your own variants. The report reads 78 genes across immune signaling and the nutrient systems behind it, looks gene by gene at the pathways that shape that balance, and ranks food-first suggestions for what it finds.
Private by design
Your DNA file stays on your computer
Your DNA file is never uploaded or stored.
The report is built inside your own web browser, on your own computer, so your file is read where it already is. Privacy is enforced by architecture, not by a policy you have to trust.
No. You pay once for this report, and there's nothing to renew or cancel.
Will it work with my DNA file?
Raw data files from 23andMe, Ancestry, MyHeritage and SelfDecode work today. Tested somewhere else? Email info@noorns.com and we'll tell you whether your file works.
What if I don't have a DNA file yet?
You need raw data from 23andMe, Ancestry, MyHeritage, or another DNA service. We do not sell kits, so order a test from one of them first, then download your raw data file from their site.
Can I do it on my phone?
For now, generating your report works best on a computer. Once it's ready, you can read the PDF on any device.
What if my file doesn't work, or a run doesn't finish?
Each purchase includes up to three report runs, for a retry, a lost PDF or an updated version. If your file can't produce a report, we'll reset your run or refund you. If something else goes wrong, email info@noorns.com and we'll do our best to make it right.
Can I get a refund?
Yes. You can get a refund within 14 days of purchase if you haven't accessed or started generating your report. If your file can't produce a report, we'll reset your run or refund you. Email info@noorns.com.
Will my report update when new research comes out?
Yes, when we update the report. Each purchase includes up to three report runs, for a retry, a lost PDF or an updated version. If we add new research while you still have a run left, run it again and you get the new version.
Do I need to be an expert to use it?
No. Most people read the Recommendations Summary, change a few things starting with food, and give it time. The gene pages and Science Deep Dive are there for when you want to go deeper, or when you are working through the results with a practitioner.
Will the report tell me whether I am Th1 or Th2 dominant?
It shows which way your genes are likely to push each part of the system, gene by gene, and ranks the foods and nutrients that fit. It does not measure which mode your immune system is in right now. That also depends on infections, food, stress, and other triggers, so your symptoms and your practitioner's testing complete the picture.
Is this useful if I do not have an autoimmune diagnosis?
Yes. The report looks at the genetic tendencies behind immune balance, which are relevant to chronic inflammation, recurring flares, allergies, and lingering fatigue whether or not you have a diagnosis.
Can I use this alongside my current treatment?
Yes, and that is how it is intended. The report is designed to inform conversations with your doctor, rheumatologist, or integrative practitioner, not to replace them. Check any supplement or diet change with your healthcare provider first, especially if you take medication that acts on the immune system, such as steroids or biologics.
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