{"product_id":"stress-and-energy","title":"Stress and Energy Report","description":"\u003cdiv style=\"background:#f6f2fc;border-radius:12px;padding:18px 22px;margin:0 0 22px\"\u003e\n\u003cul style=\"margin:0;padding-left:18px\"\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eFor you if\u003c\/strong\u003e you want your stress-response genes read alongside your methylation and dietary genes, in one plan.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eYou get\u003c\/strong\u003e a PDF report built around one short, ranked list of what to eat, add, and avoid.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eYou need\u003c\/strong\u003e the raw DNA file you already have from 23andMe, Ancestry, MyHeritage, or another DNA service. No new test.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003ePrivate by design.\u003c\/strong\u003e The report runs in your browser. Your DNA is never uploaded or stored.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eReady in 3 to 10 minutes,\u003c\/strong\u003e with a 14-day refund if you have not started generating it.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"margin-top:12px\"\u003e\u003ca href=\"\/#shopify-section-template--30864476143961__section_tUjXVr\" style=\"color:#ce446e;text-decoration:underline\"\u003e\u003cstrong\u003eGet a free example report before you buy\u003c\/strong\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv\u003eIf you want to know \u003cstrong\u003ehow your genes shape your stress response\u003c\/strong\u003e and your nutrient needs, this report reads both.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv\u003eYour stress response is meant to switch on when you need it and \u003cstrong\u003eswitch off once the pressure passes\u003c\/strong\u003e. The genes behind that switch vary from person to person, and so do the genes that shape your nutrient needs. Advice written for everyone does not account for either.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTwo systems sit underneath this.\u003c\/strong\u003e The HPA axis is the chain of signals from your brain to your adrenal glands that controls cortisol, your main stress hormone. Methylation is the process that attaches small chemical tags to your DNA to turn genes up or down, and it also helps your body make neurotransmitters. The two are linked, because research suggests methylation on some stress genes can affect how well the stress response switches off.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv\u003eThis report reads the genes behind both systems, along with the dietary genetics that shape your nutrient needs, and turns them into \u003cstrong\u003eone ranked, food-first plan\u003c\/strong\u003e.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ch3\u003eHow this report compares\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli style=\"margin-bottom:1em\"\u003e\u003cspan\u003e\u003cstrong\u003eMethylation and Diet Report.\u003c\/strong\u003e The methylation cycle, neurotransmitter and histamine clearance, vitamin needs, and dietary genetics.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"margin-bottom:1em\"\u003e\u003cspan\u003e\u003cstrong\u003eStress and Energy Report.\u003c\/strong\u003e Nearly all of the Methylation and Diet genes, plus five stress-response genes (CRHR1, CRHR2, POMC, NR3C1, FKBP5) and a Science Deep Dive on the HPA axis. If you own the Methylation and Diet Report, those five genes and the HPA deep dive are what this adds.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"margin-bottom:1em\"\u003e\u003cspan\u003e\u003cstrong\u003eAnxiety and Calm Report.\u003c\/strong\u003e Every gene in this report, plus the GABA, serotonin, dopamine, oxytocin, adenosine, and BDNF genes. If you own the Anxiety and Calm Report, this report adds no new genes.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy the same stress protocol works differently for different people\u003c\/h3\u003e\n\u003cdiv\u003eThree examples from this report:\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eNR3C1, FKBP5 and the cortisol off-switch.\u003c\/strong\u003e NR3C1 makes the glucocorticoid receptor, which cortisol binds to tell the brain to wind the stress response down. FKBP5 makes that receptor less sensitive, so higher FKBP5 levels can weaken the off-switch. In one study, a common FKBP5 variant raised the risk of stress-related conditions only in adults who faced childhood trauma, seemingly through lasting chemical tags on the gene without changing the DNA. For these genes, the report suggests regular stress-reduction practices such as meditation, yoga, or massage, omega-3 fats, and keeping vitamin D out of the low range. Your file shows the variant but not your history, and the study did not test these general supports.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eMTHFR, COMT and methyl balance.\u003c\/strong\u003e MTHFR's enzyme makes the active folate your methylation cycle runs on and needs riboflavin (vitamin B2). Two copies of a common variant make it less active. In a randomized trial, riboflavin lowered homocysteine, a marker of how well the cycle works, by 22 percent in people with two copies, with no effect in people carrying one copy or none. The report also reads COMT, since methyl-donor tolerance depends partly on how fast COMT clears stress chemicals like adrenaline, and suggests sensitive people start B vitamins at very low doses.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eFADS1 and omega-3.\u003c\/strong\u003e FADS1 helps turn the omega-3 in plant foods into EPA, a longer omega-3 fat. In a genome-wide study, a common variant near FADS1, which this report reads, was strongly associated with blood levels of EPA and other fatty acids. For carriers, the report leans toward fatty fish and a Mediterranean or pescatarian pattern instead of relying on plant sources alone, and away from seed oils high in linoleic acid.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv\u003eThose are three of the mechanisms. The report covers 65 genes across seven pathways.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ch3\u003eWhat the report analyzes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eThe HPA axis and cortisol regulation.\u003c\/strong\u003e Variants studied in cortisol signaling and feedback (CRHR1, CRHR2, POMC, NR3C1, FKBP5).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eThe methylation cycle.\u003c\/strong\u003e Genes studied in making and recycling methyl groups, which the report uses to set your needs for folate, B12, riboflavin, B6, and choline (SLC19A1, DHFR, MTHFS, MTHFD1, MTHFR, MTR, MTRR, PEMT, BHMT, AHCY, CBS, COMT).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eNeurotransmitter and histamine clearance.\u003c\/strong\u003e Genes studied in breaking down serotonin, dopamine, adrenaline, and histamine (MAOA, MAOB, HNMT, AOC1\/DAO, ALDH2, FMO3).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eSulfur, detoxification and protein handling.\u003c\/strong\u003e How you process sulfur compounds, build glutathione, clear certain chemicals and medicines, and handle the nitrogen from protein (SUOX, GSS, NAT1, NAT2, CYP1A2, CPS1).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eVitamin and mineral needs.\u003c\/strong\u003e How efficiently you activate and use vitamins D, A, B6, and B12, and how you absorb and store iron (CYP2R1, GC, VDR, BCO1, FUT2, NBPF3, HFE, TF, TMPRSS6).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eDietary and metabolic genetics.\u003c\/strong\u003e How your body handles fat, carbohydrate, fructose, and lactose (FADS1, FADS2, ADIPOQ, PGC-1α, PPARG, PPARA, PPARGC1B, ACAT1, LIPC, APOE, CETP, APOA2, FTO, LEPR, IRS1, LCT, CLTCL1, ALDOB).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eBlood pressure, uric acid and oxalate.\u003c\/strong\u003e Genes linked to blood pressure, cholesterol particles, uric acid, and the oxalate that can form kidney stones (ACE, AGT, LPA, SLC2A9, ABCG2, SPP1, AGXT, GRHPR, HOGA1).\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhat you get\u003c\/h3\u003e\n\u003cdiv\u003eEvery Noorns report follows the same structure, built to cut through overwhelm and point you to action:\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eA Recommendations Summary.\u003c\/strong\u003e A short, ranked list of foods, nutrients, and lifestyle factors to \u003cstrong\u003efocus on or avoid\u003c\/strong\u003e, scored by the combined strength of your genetic signal. The place to start.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eA Conflicts section.\u003c\/strong\u003e Where genes pull in opposite directions on the same intervention, both scores are shown so you and your practitioner can make an informed call.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eGene-by-gene pages.\u003c\/strong\u003e Plain-English explanations of every gene, your specific variants, and the targeted changes tied to each one.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eA Science Deep Dive.\u003c\/strong\u003e The full biology of the HPA axis and cortisol, the methylation cycle, choline and riboflavin, and how methylation shapes the stress response, for when you or your practitioner want to go deeper.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWho it is for\u003c\/h3\u003e\n\u003cdiv\u003eThis report is for people who want their stress-response genes read together with their methylation and dietary genes, and turned into one plan they can act on or bring to a practitioner.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv\u003eThe same DNA file powers every Noorns report.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ch3\u003eYour DNA file never leaves your computer\u003c\/h3\u003e\n\u003cdiv\u003eWhen you generate this report, the analysis runs entirely inside your own web browser, on your own device. We do not upload your DNA. We do not store it. We cannot read it. Privacy is enforced by architecture, not by a policy you have to trust.\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ch3\u003eHow it works\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eBuy the report.\u003c\/strong\u003e You get a sign-in link by email. There is no password to remember.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eAdd your DNA file.\u003c\/strong\u003e Select the raw data file you already have from 23andMe, Ancestry, MyHeritage, or another DNA service. It is read on your computer and never sent to us.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eGenerate and save.\u003c\/strong\u003e The analysis takes three to ten minutes in your browser, then hands you a PDF to keep. Keep the tab open while it runs.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003eA note on medical care\u003c\/h3\u003e\n\u003cdiv\u003eThis report is education about your genes and your nutrition. It does not diagnose any condition or measure your cortisol. Talk to your doctor before you start a supplement or change a medication.\u003c\/div\u003e\n","brand":"Noorns","offers":[{"title":"Default Title","offer_id":56467808977241,"sku":"15893040824665","price":39.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0972\/8183\/5353\/files\/noorns-gallery-hpa-axis-methylation-1.jpg?v=1791544619","url":"https:\/\/noorns.com\/products\/stress-and-energy","provider":"Noorns NuGen","version":"1.0","type":"link"}